S21F (p.Ser21Phe) variant of APC (Adenomatous polyposis coli protein)
S21F (p.Ser21Phe) in APC (Adenomatous polyposis coli protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
S21F (p.Ser21Phe) variant details
- p.Ser21Phe
- rs770241997
- gnomAD 5-112707788-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.244
- REVEL 0.15
- CADD 17.50
- Most common in the HGDP:SAN population (allele frequency 1)
- Structural context available
- Literature evidence available