R24S (p.Arg24Ser) variant of APC (Adenomatous polyposis coli protein)
R24S (p.Arg24Ser) in APC (Adenomatous polyposis coli protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
R24S (p.Arg24Ser) variant details
- p.Arg24Ser
- rs1242659289
- gnomAD 5-112707810-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.198
- REVEL 0.11
- CADD 17.20
- Most common in the HGDP:CAMBODIAN population (allele frequency 0.25)
- Structural context available
- Literature evidence available