R24C (p.Arg24Cys) variant of APC (Adenomatous polyposis coli protein)
R24C (p.Arg24Cys) in APC (Adenomatous polyposis coli protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
R24C (p.Arg24Cys) variant details
- p.Arg24Cys
- rs755954869
- gnomAD 5-112707850-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.394
- REVEL 0.17
- CADD 21.30
- Most common in the Ashkenazi Jewish population (allele frequency 0.0052)
- Structural context available
- Literature evidence available