Q25K (p.Gln25Lys) variant of APC (Adenomatous polyposis coli protein)
Q25K (p.Gln25Lys) in APC (Adenomatous polyposis coli protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
Q25K (p.Gln25Lys) variant details
- p.Gln25Lys
- gnomAD rs1231069533
- Missense
- Variant Prioritization Score for Impact Estimate 0.388
- REVEL 0.25
- ESM-1b 0.00
- AlphaMissense 0.13
- MetaLR 0.08
- MetaSVM -1.03
- CADD 24.60
- Most common in the HGDP:TUSCAN population (allele frequency 1)
- Structural context available