Q25* (p.Gln25Ter) variant of APC (Adenomatous polyposis coli protein)
Q25* (p.Gln25Ter) in APC (Adenomatous polyposis coli protein) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, published literature, and structural context.
Q25* (p.Gln25Ter) variant details
- p.Gln25Ter
- rs773941688
- gnomAD 5-112707823-C-T
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.51
- CADD 35.00
- Most common in the HGDP:YORUBA population (allele frequency 0.024)
- Structural context available
- Literature evidence available