L9F (p.Leu9Phe) variant of APC (Adenomatous polyposis coli protein)
L9F (p.Leu9Phe) in APC (Adenomatous polyposis coli protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
L9F (p.Leu9Phe) variant details
- p.Leu9Phe
- Ensembl rs2149737508
- Missense
- Variant Prioritization Score for Impact Estimate 0.578
- REVEL 0.45
- ESM-1b 1.00
- AlphaMissense 0.99
- MetaLR 0.15
- MetaSVM -0.91
- CADD 27.10
- Most common in the 1KG:YRI population (allele frequency 0.0043)
- Structural context available