L27Q (p.Leu27Gln) variant of APC (Adenomatous polyposis coli protein)
L27Q (p.Leu27Gln) in APC (Adenomatous polyposis coli protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes structural context.
L27Q (p.Leu27Gln) variant details
- p.Leu27Gln
- Ensembl rs2149738192
- Missense
- Variant Prioritization Score for Impact Estimate 0.466
- REVEL 0.47
- ESM-1b 0.75
- AlphaMissense 0.99
- MetaLR 0.16
- MetaSVM -0.84
- SIFT 0.00
- Structural context available