L27L (p.Leu27Leu) variant of APC (Adenomatous polyposis coli protein)
L27L (p.Leu27Leu) in APC (Adenomatous polyposis coli protein) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
L27L (p.Leu27Leu) variant details
- p.Leu27Leu
- rs759312196
- gnomAD 5-112754971-A-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.282
- CADD 9.37
- Most common in the 1KG:ACB population (allele frequency 0.0054)
- Structural context available
- Literature evidence available