K17N (p.Lys17Asn) variant of APC (Adenomatous polyposis coli protein)
K17N (p.Lys17Asn) in APC (Adenomatous polyposis coli protein) is a missense change. Clinical records from EBI and UniProt describe it as likely benign. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
K17N (p.Lys17Asn) variant details
- p.Lys17Asn
- Ensembl rs1554067118
- Likely benign
- Missense
- Variant Prioritization Score for Impact Estimate 0.574
- ESM-1b 0.29
- AlphaMissense 0.98
- CADD 20.30
- SIFT 0.38
- EBI: Likely benign
- UniProt: Likely benign
- Population evidence available
- Structural context available