H33P (p.His33Pro) variant of APC (Adenomatous polyposis coli protein)
H33P (p.His33Pro) in APC (Adenomatous polyposis coli protein) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
H33P (p.His33Pro) variant details
- p.His33Pro
- rs1191401517
- gnomAD 5-112707863-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.371
- REVEL 0.12
- CADD 17.40
- Most common in the HGDP:BEDOUIN population (allele frequency 0.012)
- Structural context available
- Literature evidence available