E26D (p.Glu26Asp) variant of APC (Adenomatous polyposis coli protein)
E26D (p.Glu26Asp) in APC (Adenomatous polyposis coli protein) is a missense change. Clinical records from EBI and UniProt describe it as benign. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
E26D (p.Glu26Asp) variant details
- p.Glu26Asp
- Ensembl rs1561444861
- Benign
- Missense
- Variant Prioritization Score for Impact Estimate 0.59
- ESM-1b 0.00
- AlphaMissense 0.95
- CADD 21.70
- SIFT 0.05
- EBI: Benign
- UniProt: Benign
- Population evidence available
- Structural context available