S31F (p.Ser31Phe) variant of ALK (ALK tyrosine kinase receptor)
S31F (p.Ser31Phe) in ALK (ALK tyrosine kinase receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
S31F (p.Ser31Phe) variant details
- p.Ser31Phe
- Ensembl rs2148443930
- Missense
- Variant Prioritization Score for Impact Estimate 0.214
- REVEL 0.03
- MetaLR 0.24
- MetaSVM -0.90
- CADD 21.20
- PolyPhen-2 0.08
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 2.3e-05)
- Structural context available