L6P (p.Leu6Pro) variant of ALK (ALK tyrosine kinase receptor)
L6P (p.Leu6Pro) in ALK (ALK tyrosine kinase receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
L6P (p.Leu6Pro) variant details
- p.Leu6Pro
- Ensembl rs2148444157
- Missense
- Variant Prioritization Score for Impact Estimate 0.237
- REVEL 0.11
- MetaLR 0.32
- MetaSVM -0.84
- CADD 19.80
- PolyPhen-2 0.00
- SIFT 0.00
- Population evidence available
- Structural context available