L38P (p.Leu38Pro) variant of ALK (ALK tyrosine kinase receptor)
L38P (p.Leu38Pro) in ALK (ALK tyrosine kinase receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
L38P (p.Leu38Pro) variant details
- p.Leu38Pro
- Ensembl rs2148443878
- Missense
- Variant Prioritization Score for Impact Estimate 0.229
- REVEL 0.06
- MetaLR 0.24
- MetaSVM -0.82
- CADD 23.10
- PolyPhen-2 0.00
- SIFT 0.05
- Population evidence available
- Structural context available