L12V (p.Leu12Val) variant of ALK (ALK tyrosine kinase receptor)
L12V (p.Leu12Val) in ALK (ALK tyrosine kinase receptor) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of Hereditary cancer-predisposing syndrome. The record also includes structural context.
L12V (p.Leu12Val) variant details
- p.Leu12Val
- Ensembl rs2148444097
- Uncertain significance
- Hereditary cancer-predisposing syndrome
- Missense
- ClinVar: Uncertain significance (Hereditary cancer-predisposing syndrome)
- EBI: Likely benign
- UniProt: Likely benign
- Structural context available