A17V (p.Ala17Val) variant of ALK (ALK tyrosine kinase receptor)
A17V (p.Ala17Val) in ALK (ALK tyrosine kinase receptor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
A17V (p.Ala17Val) variant details
- p.Ala17Val
- Ensembl rs2148444051
- Missense
- Variant Prioritization Score for Impact Estimate 0.318
- REVEL 0.04
- MetaLR 0.27
- MetaSVM -0.89
- CADD 15.40
- PolyPhen-2 0.00
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available