V66L (p.Val66Leu) variant of ALDOB (Fructose-bisphosphate aldolase B)
V66L (p.Val66Leu) in ALDOB (Fructose-bisphosphate aldolase B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
V66L (p.Val66Leu) variant details
- p.Val66Leu
- ExAC rs772436722
- TOPMed rs772436722
- gnomAD rs772436722
- Missense
- Variant Prioritization Score for Impact Estimate 0.345
- CADD 17.70
- PolyPhen-2 0.04
- SIFT 0.03
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available