N26K (p.Asn26Lys) variant of ALDOB (Fructose-bisphosphate aldolase B)
N26K (p.Asn26Lys) in ALDOB (Fructose-bisphosphate aldolase B) is a missense change. Clinical records from EBI and UniProt describe it as likely benign. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
N26K (p.Asn26Lys) variant details
- p.Asn26Lys
- cosmic curated COSV66398
- gnomAD rs1180910257
- Likely benign
- Missense
- Variant Prioritization Score for Impact Estimate 0.648
- CADD 22.20
- PolyPhen-2 0.01
- SIFT 0.05
- EBI: Likely benign
- UniProt: Likely benign
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available