I23L (p.Ile23Leu) variant of ALDOB (Fructose-bisphosphate aldolase B)
I23L (p.Ile23Leu) in ALDOB (Fructose-bisphosphate aldolase B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
I23L (p.Ile23Leu) variant details
- p.Ile23Leu
- gnomAD rs1428910288
- Missense
- Variant Prioritization Score for Impact Estimate 0.507
- CADD 22.50
- PolyPhen-2 0.23
- SIFT 0.23
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available