F64C (p.Phe64Cys) variant of ALDOB (Fructose-bisphosphate aldolase B)
F64C (p.Phe64Cys) in ALDOB (Fructose-bisphosphate aldolase B) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes structural context.
F64C (p.Phe64Cys) variant details
- p.Phe64Cys
- rs151219186
- ESP rs151219186
- TOPMed rs151219186
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.811
- AlphaMissense 0.74
- MetaLR 0.84
- MetaSVM 0.88
- PolyPhen-2 0.94
- SIFT 0.00
- EVE 0.63
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available