F59L (p.Phe59Leu) variant of ALDOB (Fructose-bisphosphate aldolase B)
F59L (p.Phe59Leu) in ALDOB (Fructose-bisphosphate aldolase B) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
F59L (p.Phe59Leu) variant details
- p.Phe59Leu
- ExAC rs777050401
- gnomAD rs777050401
- Missense
- Variant Prioritization Score for Impact Estimate 0.592
- CADD 23.10
- PolyPhen-2 0.07
- SIFT 0.16
- Most common in the South Asian population (allele frequency 2.3e-05)
- Structural context available