W73R (p.Trp73Arg) variant of ADCY5 (Adenylate cyclase type 5)
W73R (p.Trp73Arg) in ADCY5 (Adenylate cyclase type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
W73R (p.Trp73Arg) variant details
- p.Trp73Arg
- ExAC rs779269584
- TOPMed rs779269584
- gnomAD rs779269584
- Missense
- Variant Prioritization Score for Impact Estimate 0.467
- REVEL 0.47
- MetaLR 0.37
- MetaSVM -0.27
- CADD 25.20
- PolyPhen-2 0.55
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 3.5e-05)
- Structural context available