W73G (p.Trp73Gly) variant of ADCY5 (Adenylate cyclase type 5)
W73G (p.Trp73Gly) in ADCY5 (Adenylate cyclase type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
W73G (p.Trp73Gly) variant details
- p.Trp73Gly
- ExAC rs779269584
- TOPMed rs779269584
- gnomAD rs779269584
- Missense
- Variant Prioritization Score for Impact Estimate 0.447
- REVEL 0.44
- MetaLR 0.32
- MetaSVM -0.56
- CADD 24.10
- PolyPhen-2 0.42
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available