S37A (p.Ser37Ala) variant of ADCY5 (Adenylate cyclase type 5)
S37A (p.Ser37Ala) in ADCY5 (Adenylate cyclase type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
S37A (p.Ser37Ala) variant details
- p.Ser37Ala
- TOPMed rs908234617
- gnomAD rs908234617
- Missense
- Variant Prioritization Score for Impact Estimate 0.218
- REVEL 0.17
- MetaLR 0.23
- MetaSVM -0.96
- CADD 16.40
- PolyPhen-2 0.00
- SIFT 0.12
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available