R98S (p.Arg98Ser) variant of ADCY5 (Adenylate cyclase type 5)
R98S (p.Arg98Ser) in ADCY5 (Adenylate cyclase type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
R98S (p.Arg98Ser) variant details
- p.Arg98Ser
- ExAC rs749408400
- TOPMed rs749408400
- gnomAD rs749408400
- Missense
- Variant Prioritization Score for Impact Estimate 0.488
- REVEL 0.39
- MetaLR 0.31
- MetaSVM -0.43
- CADD 24.00
- PolyPhen-2 0.07
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available