R29H (p.Arg29His) variant of ADCY5 (Adenylate cyclase type 5)
R29H (p.Arg29His) in ADCY5 (Adenylate cyclase type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
R29H (p.Arg29His) variant details
- p.Arg29His
- TOPMed rs1945871408
- Missense
- Variant Prioritization Score for Impact Estimate 0.44
- REVEL 0.32
- MetaLR 0.43
- MetaSVM -0.04
- CADD 24.70
- PolyPhen-2 0.56
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 4.3e-05)
- Structural context available