P46L (p.Pro46Leu) variant of ADCY5 (Adenylate cyclase type 5)
P46L (p.Pro46Leu) in ADCY5 (Adenylate cyclase type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
P46L (p.Pro46Leu) variant details
- p.Pro46Leu
- TOPMed rs1357790160
- gnomAD rs1357790160
- Missense
- Variant Prioritization Score for Impact Estimate 0.329
- REVEL 0.23
- MetaLR 0.22
- MetaSVM -0.73
- CADD 22.70
- PolyPhen-2 0.08
- SIFT 0.09
- Population evidence available
- Structural context available