P22S (p.Pro22Ser) variant of ADCY5 (Adenylate cyclase type 5)
P22S (p.Pro22Ser) in ADCY5 (Adenylate cyclase type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
P22S (p.Pro22Ser) variant details
- p.Pro22Ser
- TOPMed rs1945872086
- Missense
- Variant Prioritization Score for Impact Estimate 0.154
- REVEL 0.14
- MetaLR 0.16
- MetaSVM -1.01
- CADD 7.89
- PolyPhen-2 0.00
- SIFT 0.55
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available