G91R (p.Gly91Arg) variant of ADCY5 (Adenylate cyclase type 5)
G91R (p.Gly91Arg) in ADCY5 (Adenylate cyclase type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
G91R (p.Gly91Arg) variant details
- p.Gly91Arg
- ExAC rs772055808
- TOPMed rs772055808
- gnomAD rs772055808
- Missense
- Variant Prioritization Score for Impact Estimate 0.283
- REVEL 0.19
- MetaLR 0.22
- MetaSVM -0.82
- CADD 17.60
- PolyPhen-2 0.00
- SIFT 0.47
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)
- Structural context available