G52R (p.Gly52Arg) variant of ADCY5 (Adenylate cyclase type 5)
G52R (p.Gly52Arg) in ADCY5 (Adenylate cyclase type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
G52R (p.Gly52Arg) variant details
- p.Gly52Arg
- TOPMed rs1945869596
- Missense
- Variant Prioritization Score for Impact Estimate 0.335
- REVEL 0.15
- MetaLR 0.20
- MetaSVM -0.80
- CADD 19.50
- PolyPhen-2 0.09
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 9.6e-07)
- Structural context available