A90V (p.Ala90Val) variant of ADCY5 (Adenylate cyclase type 5)
A90V (p.Ala90Val) in ADCY5 (Adenylate cyclase type 5) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
A90V (p.Ala90Val) variant details
- p.Ala90Val
- TOPMed rs1338819669
- gnomAD rs1338819669
- Missense
- Variant Prioritization Score for Impact Estimate 0.151
- REVEL 0.17
- MetaLR 0.15
- MetaSVM -1.01
- CADD 3.05
- PolyPhen-2 0.00
- SIFT 0.18
- Most common in the Latino/Admixed American population (allele frequency 2.8e-05)
- Structural context available