W98R (p.Trp98Arg) variant of ACVR1 (Activin receptor type-1)
W98R (p.Trp98Arg) in ACVR1 (Activin receptor type-1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
W98R (p.Trp98Arg) variant details
- p.Trp98Arg
- cosmic curated COSV55115
- Missense
- Variant Prioritization Score for Impact Estimate 0.544
- REVEL 0.51
- CADD 24.30
- PolyPhen-2 0.00
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available