W69G (p.Trp69Gly) variant of ABCA1 (O95477)
W69G (p.Trp69Gly) in ABCA1 (O95477) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.86 / 1. The record also includes population frequency data and structural context.
W69G (p.Trp69Gly) variant details
- p.Trp69Gly
- ExAC rs756278529
- gnomAD rs756278529
- Missense
- Variant Prioritization Score for Impact Estimate 0.864
- REVEL 0.95
- MetaLR 0.99
- MetaSVM 0.93
- CADD 32.00
- PolyPhen-2 0.89
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available