W4C (p.Trp4Cys) variant of ABCA1 (O95477)
W4C (p.Trp4Cys) in ABCA1 (O95477) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
W4C (p.Trp4Cys) variant details
- p.Trp4Cys
- TOPMed rs1221387381
- gnomAD rs1221387381
- Missense
- Variant Prioritization Score for Impact Estimate 0.528
- REVEL 0.45
- CADD 22.90
- PolyPhen-2 0.00
- SIFT 0.19
- Population evidence available
- Structural context available