W31C (p.Trp31Cys) variant of ABCA1 (O95477)
W31C (p.Trp31Cys) in ABCA1 (O95477) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.86 / 1. The record also includes population frequency data and structural context.
W31C (p.Trp31Cys) variant details
- p.Trp31Cys
- gnomAD rs1839480494
- Missense
- Variant Prioritization Score for Impact Estimate 0.862
- REVEL 0.89
- CADD 29.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available