T16S (p.Thr16Ser) variant of ABCA1 (O95477)
T16S (p.Thr16Ser) in ABCA1 (O95477) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data and structural context.
T16S (p.Thr16Ser) variant details
- p.Thr16Ser
- gnomAD rs1466089023
- Missense
- Variant Prioritization Score for Impact Estimate 0.694
- REVEL 0.63
- CADD 25.90
- PolyPhen-2 0.86
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 2.4e-05)
- Structural context available