N141S (p.Asn141Ser) variant of ABCA1 (O95477)
N141S (p.Asn141Ser) in ABCA1 (O95477) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
N141S (p.Asn141Ser) variant details
- p.Asn141Ser
- gnomAD rs1178234418
- Missense
- Variant Prioritization Score for Impact Estimate 0.331
- REVEL 0.22
- MetaLR 0.56
- MetaSVM -0.42
- CADD 13.60
- PolyPhen-2 0.00
- SIFT 0.24
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available