N141D (p.Asn141Asp) variant of ABCA1 (O95477)
N141D (p.Asn141Asp) in ABCA1 (O95477) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
N141D (p.Asn141Asp) variant details
- p.Asn141Asp
- ExAC rs748252360
- gnomAD rs748252360
- Missense
- Variant Prioritization Score for Impact Estimate 0.2
- REVEL 0.16
- MetaLR 0.55
- MetaSVM -0.38
- CADD 11.70
- PolyPhen-2 0.00
- SIFT 0.48
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available