L105P (p.Leu105Pro) variant of ABCA1 (O95477)
L105P (p.Leu105Pro) in ABCA1 (O95477) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.87 / 1. The record also includes population frequency data and structural context.
L105P (p.Leu105Pro) variant details
- p.Leu105Pro
- ExAC rs746275015
- gnomAD rs746275015
- Missense
- Variant Prioritization Score for Impact Estimate 0.867
- REVEL 0.98
- MetaLR 0.95
- MetaSVM 1.10
- CADD 29.00
- PolyPhen-2 0.98
- SIFT 0.00
- Population evidence available
- Structural context available