F106L (p.Phe106Leu) variant of ABCA1 (O95477)
F106L (p.Phe106Leu) in ABCA1 (O95477) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
F106L (p.Phe106Leu) variant details
- p.Phe106Leu
- ExAC rs774529961
- gnomAD rs774529961
- Missense
- Variant Prioritization Score for Impact Estimate 0.502
- REVEL 0.56
- MetaLR 0.72
- MetaSVM 0.32
- CADD 18.30
- PolyPhen-2 0.00
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available