F106I (p.Phe106Ile) variant of ABCA1 (O95477)
F106I (p.Phe106Ile) in ABCA1 (O95477) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.71 / 1. The record also includes population frequency data and structural context.
F106I (p.Phe106Ile) variant details
- p.Phe106Ile
- ExAC rs774529961
- gnomAD rs774529961
- Missense
- Variant Prioritization Score for Impact Estimate 0.709
- REVEL 0.72
- MetaLR 0.92
- MetaSVM 1.05
- CADD 23.40
- PolyPhen-2 0.21
- SIFT 0.01
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available