D150N (p.Asp150Asn) variant of ABCA1 (O95477)
D150N (p.Asp150Asn) in ABCA1 (O95477) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data and structural context.
D150N (p.Asp150Asn) variant details
- p.Asp150Asn
- ExAC rs766806821
- TOPMed rs766806821
- gnomAD rs766806821
- Missense
- Variant Prioritization Score for Impact Estimate 0.564
- REVEL 0.55
- MetaLR 0.90
- MetaSVM 0.97
- CADD 23.10
- PolyPhen-2 0.12
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available