T8M (p.Thr8Met) variant of ZRSR2 (Q15696)
T8M (p.Thr8Met) in ZRSR2 (Q15696) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.08 / 1. The record also includes population frequency data and structural context.
T8M (p.Thr8Met) variant details
- p.Thr8Met
- ExAC rs747435591
- gnomAD rs747435591
- Missense
- Variant Prioritization Score for Impact Estimate 0.0816
- REVEL 0.02
- MetaLR 0.02
- MetaSVM -1.02
- CADD 7.07
- PolyPhen-2 0.00
- SIFT 0.47
- Most common in the Non-Finnish European population (allele frequency 4.9e-06)
- Structural context available