L42I (p.Leu42Ile) variant of ZRSR2 (Q15696)
L42I (p.Leu42Ile) in ZRSR2 (Q15696) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
L42I (p.Leu42Ile) variant details
- p.Leu42Ile
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.319
- REVEL 0.10
- MetaLR 0.54
- MetaSVM -0.51
- CADD 14.00
- PolyPhen-2 0.02
- SIFT 0.59
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available