K45E (p.Lys45Glu) variant of ZRSR2 (Q15696)
K45E (p.Lys45Glu) in ZRSR2 (Q15696) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
K45E (p.Lys45Glu) variant details
- p.Lys45Glu
- gnomAD rs1476833485
- Missense
- Variant Prioritization Score for Impact Estimate 0.119
- REVEL 0.06
- MetaLR 0.28
- MetaSVM -0.83
- CADD 6.08
- PolyPhen-2 0.01
- SIFT 0.66
- Most common in the Latino/Admixed American population (allele frequency 5.7e-05)
- Structural context available