A21S (p.Ala21Ser) variant of ZRSR2 (Q15696)
A21S (p.Ala21Ser) in ZRSR2 (Q15696) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
A21S (p.Ala21Ser) variant details
- p.Ala21Ser
- gnomAD X-15790953-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.138
- REVEL 0.03
- MetaLR 0.06
- MetaSVM -1.02
- CADD 16.60
- PolyPhen-2 0.01
- SIFT 0.32
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available
- Literature evidence available