Q27K (p.Gln27Lys) variant of YAP1 (Transcriptional coactivator YAP1)
Q27K (p.Gln27Lys) in YAP1 (Transcriptional coactivator YAP1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
Q27K (p.Gln27Lys) variant details
- p.Gln27Lys
- gnomAD 11-102110927-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.212
- REVEL 0.05
- CADD 15.70
- PolyPhen-2 0.00
- SIFT 0.59
- Most common in the South Asian population (allele frequency 1.5e-05)
- Structural context available
- YAP1 WW domain domainome 1.0: score -0.805
- Literature evidence available