Q27H (p.Gln27His) variant of YAP1 (Transcriptional coactivator YAP1)
Q27H (p.Gln27His) in YAP1 (Transcriptional coactivator YAP1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, experimental measurements, and structural context.
Q27H (p.Gln27His) variant details
- p.Gln27His
- cosmic curated COSV56776
- TOPMed rs914654817
- gnomAD rs914654817
- Missense
- Variant Prioritization Score for Impact Estimate 0.156
- REVEL 0.03
- CADD 16.30
- PolyPhen-2 0.01
- SIFT 0.13
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available
- YAP1 WW domain domainome 1.0: score -0.805