Q27A (p.Gln27Ala) variant of YAP1 (Transcriptional coactivator YAP1)
Q27A (p.Gln27Ala) in YAP1 (Transcriptional coactivator YAP1) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
Q27A (p.Gln27Ala) variant details
- p.Gln27Ala
- gnomAD 11-102110922-A-AG
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.478
- CADD 23.50
- Population evidence available
- Structural context available
- YAP1 WW domain domainome 1.0: score -0.805
- Literature evidence available