Q25K (p.Gln25Lys) variant of YAP1 (Transcriptional coactivator YAP1)
Q25K (p.Gln25Lys) in YAP1 (Transcriptional coactivator YAP1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data, experimental measurements, published literature, and structural context.
Q25K (p.Gln25Lys) variant details
- p.Gln25Lys
- gnomAD 11-102110921-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.178
- REVEL 0.06
- CADD 15.40
- PolyPhen-2 0.00
- SIFT 0.73
- Most common in the Non-Finnish European population (allele frequency 9.7e-07)
- Structural context available
- YAP1 WW domain domainome 1.0: score -0.395
- Literature evidence available